Endophytes: Microbes Living Inside the Roots and Shoots of Plants

At Intrinsyx Bio, we are commercializing 3 decades of the leading academic research in the plant microbiome. Our endophytic microbes cause crop plants, grasses, ornamental plants, and trees to fix Nitrogen (N2) directly from the atmosphere into ammonia which helps improve nutrient use efficiency, supplement synthetic fertilizer requirements, and increase chlorophyll.  These microbes live in leaves, stems, roots and don’t require a nodule.  They also mobilize insoluble phosphorus (P2) from soil into roots, and help with phosphate mobility from the roots into the shoots.

  • Increases crop yield and quality (mineral nutrition and Brix)

  • Decreases nitrogen fertilizer requirements

  • Decreases phosphorus fertilizer requirements

  • Increases crop drought, flood, and salt tolerance

  • Diverse endophyte products: seed treatment, foliar, in furrow, granular

Endophytes living inside of plant cells

Endophyte crack entry through roots

Microbial Solutions

It is well established that conventional nitrogen fertilization is only 30-50% efficient, in terms of what the plant utilizes.

The rest is lost to the environment and may result in significant pollution. Another consequence of these fertilization practices is negative impacts on plant beneficial microbes. At Intrinsyx Bio we aim to resolve this.

The Nitrogen Dilemma

A major component of the Modern Agriculture revolution has been the deployment of synthetic fertilizers, which have largely contributed to the huge improvements in crop yields over the last several decades. Nitrogenous fertilizer production accounts for approximately 2% of global energy consumption.

An unintended consequence of these modern inputs has been significant negative impacts on soil and plant microbial communities and a concomitant decrease in nutrient use efficiencies.

Nitrogen Fixation

Over every acre of farmland exists about 45 tons of nitrogen in the air, more than enough to grow any crop.  The problem is nitrogen in that form is not directly available to all plants; at least not until now.

Our collection of natural symbiotic microbes enable plants to fix nitrogen directly from the air inside the plants.  This allows plants in general to operate like legumes.  Our microbial inoculants reduce farming costs, enhance yields and help the environment.

Increased Yield and Quality

We have conducted third party validated greenhouse and field trials in over 20 types of plants, with consistently impressive results across the board.

These microbes offer their plant hosts many benefits, including increased N and P nutrient acquisition abilities which increase their size and subsequent yields.

Smart Forestry Biology

These microbes were first discovered in trees growing in nutrient poor conditions in the forests of the Pacific Northwest.

We are currently trialing with large players in the forestry industry in the Pacific Northwest and the Southeastern United States. Greenhouse trialing to date has shown astounding increases in plant growth and health.

Meet Our Directors

We have brought together some of the world’s leading researchers of plant endo-symbiotic microbes (true endophytes) to deploy a groundbreaking  and well-characterized microbial endophyte collection. Through endophyte application, growers have substantially increased yields above crops grown both in optimum soil nutrition and in nitrogen deficient soils. Our crop endophytes even increase yields under high abiotic stress-saline soil or drought conditions. We believe our products will play a key role in ensuring the sustainability of global agriculture in the 21st Century.

Arshad Mian
Arshad MianChairman
30 years managing NASA Biology research projects in collaboration with industry and international agencies
Ahsan Ali
Ahsan AliCEO
Managed science collaborations with federal agencies and Fortune 100 companies
Dr John Freeman
Dr John FreemanCSO
Led Agricultural R&D teams at USDA-ARS, Purdue, Colorado State, CSU Fresno, NASA

The Power of Plant-Microbe Partnerships

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